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    • 전공분야

      의약화학(Medicinal Chemistry)

    • 담당과목

      분자설계 (Computer Aided Drug Design)

    한철규

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    본인은 종근당 신약연구소에서 새로운 항진균제의 개발(A Study for the Development of New Antifungals ), 천연물 유래의 고형암 치료제의 개발, 항바이러스성 뉴클레오사이드의 효소적 광학분할에 관한 연구, 항바이러스제(5-methoxymethyluridine유도체의합성) 에 관한연구(A Study for the Development of Antivirals), 혈관신생억제성 항암제 fumagillin 유도체의 개발(Development of Fumagillin Derivatives, An Antiangiogenic Antitumor Agent), 캄토테신계 항암제의 임상개발연구(Clinical Development of A Camptothecin Derivatives Antitumor Agent), HCV polymerase inhibitor 연구, Cathepsin-K inhibitor 연구, HBV Antiviral nucleoside analogues 연구, -HIV-RT inhibitor 연구, Melanocortin-4 inhibitor 연구를 진행했고 2000년도에는 회사를 설립하여 Pan-Raf Inhibitor, RIPK1 Inhibitor(AD, ALS, MS, PD), Autoimmune Diseases, Fibrosis, NASH, Immuno-Oncology, CNS & Autoimmune Diseases, 섬유협착성 크론병 연구, 파킨슨병 치료제 공동 개발연구, ADC 개발 및 제조, 망막질환 치료제 공동개발 연구를 진행했다.
    주요 참여 학술단체는 대한화학회(The Korean Chemical Society), 대한생화학회(The Korean Biochemical Society), 대한약학회(The Korean Pharmaceutical Association), 대한암학회(The Korean Cancer Association) 이다.
    At the Chong Kun Dang New Drug Research Institute, I have been involved in the development of new antifungals (A Study for the Development of New Antifungals), development of solid cancer treatments derived from natural products, research on enzymatic optical cleavage of antiviral nucleosides, and antiviral drugs (5-methoxymethyluridine). A Study for the Development of Antivirals, Development of Fumagillin Derivatives, An Antiangiogenic Antitumor Agent, Clinical Development of Camptothecin Anticancer Agents A Camptothecin Derivatives Antitumor Agent), HCV polymerase inhibitor research, Cathepsin-K inhibitor research, HBV Antiviral nucleoside analogues research, -HIV-RT inhibitor research, and Melanocortin-4 inhibitor research were conducted. In 2000, the company was established and Pan-Raf Inhibitor was established. , RIPK1 Inhibitor (AD, ALS, MS, PD), Autoimmune Diseases, Fibrosis, NASH, Immuno-Oncology, CNS & Autoimmune Diseases, fibrostenotic Crohn's disease research, Parkinson's disease treatment joint development research, ADC development and manufacturing, retinal disease We conducted joint development research on treatments.
    The major participating academic organizations are The Korean Chemical Society, The Korean Biochemical Society, The Korean Pharmaceutical Association, and The Korean Cancer Association.
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    • 전공분야

      구조생물학

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    SML바이오팜 연구소장
    	
    																
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    소속 Yale School of Medicine
    학과 Department of Comparative Medicine
    직위 Associate Research Scientist (연구 Faculty)